Background: Patient-doctor relationship and patient satisfaction are important engines that improve patient compliance and hence the health outcome. There are widely used instruments to measure patient-doctor relationship and patient satisfaction for primary health care purposes. Researchers lack a validated Arabic instrument that is tailored to the Arab population. So, it is important to translate and validate Patient-Doctor Relationship (PDRQ9) and patient satisfaction (PSQ 18) questionnaires into the Arabic language. Objectives: Is therefore to develop, evaluate, and validate a self-reported measure of Patient-Doctor Relationship (PDRQ9) and patient satisfaction (PSQ 18). Subject and Method: The Arabic version of PDRQ-9 and the PSQ-18 was translated from the English one with back to back translation. They were pilot tested statistically to ensure the psychometric properties (reliability and validity) and the appropriateness for the adult participants in the Arab countries. The Arabic questionnaires were administered to 434 adult participant attending primary health care facilities and hospitals in Suez Governorate, Egypt. Results: Exploratory factor analysis suggested two factors, comprising of 27 items in total. Good model fit was demonstrated through confirmatory factor analysis, with measurement invariance analyses demonstrating equivalent factor structures across. Internal consistency for the PDRQ-9 ranged between (α= 0.981-0.975) for the total scores and that for PSQ-18 ranged between (α = 0.986-0.984). Conclusion: Initial testing of the Arabic versions of the PDRQ-9 and PSQ-18 suggests that these questionnaires have satisfactory psychometric properties.