Background: The complexity of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) makes the clinical course of the disease develop rapidly, causing severe and deadly complications. Identifying effective laboratory biomarkers able to predicting patients based on their risk. This study aimed to look for those serobiomarkers in hospitalized patients with Coronavirus Disease 2019 (COVID‐19). Materials and Methods: In this retrospective observational study, 114 patients with COVID-19, admitted to Valian hospital in Aligudarz, City, Iran from October to December 2020 were examined. The disease outcome was followed along with the hospital course of every patient at the time of analysis. Laboratory investigations of all patients were monitored at the time of admission. A comparative analysis was done between the survivors (n=73) and non-survivors (n=41). Statistical analysis was conducted using SPSS. Results: Of the 114 patients, 40.4% (n=41) were non-survivor, and there were significant differences in Hemoglobin (Hb), Hematocrit (Hct), Platelet (PLT), Alkaline Phosphatase (ALP), Total Bilirubin, Fasting Blood Suger (FBS), Total Iron-Binding Capacity (TIBC), Lactate Dehydrogenase (LDH), Blood Urea Nitrogen (BUN), Creatinine (Cr), Albumin (ALB), and C-Reactive Protein (CRP) between survivors and non-survivors. Conclusion: The laboratory parameters have fundamental roles in poor prognosis and mortality prediction rated among patients with COVID-19 in the first admission. Thus, it is highly recommended to collaborate among hematologists, health managers, and clinical especialists.

We want to evaluate the effect of Allium noeanum Reut. ex Regel (Bonsor) known (traditional medicine agent) in calcium oxalate stones in kidney. 36 male rats were divided into 6 groups. I: healthy model + water, II: negative model + 1% ethylene glycol in water, III: 750 mg/kg of total extract +1% of ethylene glycol in water(Prevention), IV: 250 mg/kg flavonoid extract +1% of ethylene glycol in water (Prevention), V: 1500 mg/kg of total extract from 15th day+ 1% of ethylene glycol in water (Treatment), VI: 500 mg/kg of flavonoid extract from 15th of the study + 1% of ethylene glycol in water (Treatment).24-hour urine and blood samples were collected in 30th day for analysis. Pathology of kidneys was checked. Serum urea, uric acid, creatinine and urine calcium and oxalate were significantly increased, urine citrate was decreased in group II Vs I. (P < .05). Extract administration significantly decreased serum creatinine, urea and uric acid. Urine calcium and oxalate significantly decreased in treated groups. Urine calcium levels were significantly decreased in treated rats, but urine citrate levels were increased Vs group II. (P < .05). No crystal accumulation and tubular cast were observed in prevention groups. Hydroalcholic extract of Allium noeanum was able to reduce urine oxalate.

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