Traditional medical care systems are believed to incorporate natural ingredients into potential medicines. Lack of standardization has led Ayurveda as a marginalized medical practice. This study aims to throw some light on selected fermented polyherbal formulations against a rare but fatal infection causing C. violaceum and intestinal E. coli flora. The process of fermentation transforms the actual phytochemicals into a therapeutic molecule. Alcohol produced as a result of fermentation and the phytochemicals exhibits an antibacterial property. Determination of phytochemicals in the formulations and alcohol content makes bacteria and helminths susceptible to the treatment. Phenols, alkaloids and steroids were found to be positive for all the formulations, i.e., Chandanasava, Punarnavasava and Vidangarishta. Assessment of fermented Ayurvedic formulation reveals that it is a potent vermifuge with the goodness of nature. Among the formulations Vidangarishta was found to be most potent in paralysing worms. The results of the study implicate cytotoxic effects of these formulations against C. violaceum and intestinal E. coli flora and also their ability to act as an anthelminthic agents.

Ayurveda is an ancient traditional medical care system. The major aim of Ayurveda is to prevent unnecessary suffering and aiding healthy long life. Ayurveda incorporates natural constituents to make potential medicines that are believed to eliminate the root cause of the diseases. Forty-five thousand plant species are found in the subcontinent of India making it one of the largest biodiversity centers. In India alone, 15,000 medicinal plant species have been reported out of which 7500 species are used by the communities to cure different diseases. Ayurveda uses single or polyherbal for treatment. In these traditional medicine systems, various formulations are prepared one of which is fermented formulations, namely, arishtas and asavas. These formulations are prepared using a decoction of herbal drugs and contain self-generated alcohol. Fermented formulations are known for their stability and efficacy. Indian traditional literature states the usage of these formulations regularly with scientific validation strengthens one immunity and well-being. The current review focuses on Vidangarishta. Punarnavasava, Chandanasava, their preparations, therapeutics uses, and their toxic effects. A thorough understating of these formulations aids in standardizing Ayurveda as a marginalized medicine.