In long-term haemodialysis patients suffering from secondary hyperparathyroidism Se iPTH could be suppressed by an intravenous calcitriol therapy. As the Se iPTH level became reduced, lower doses of Rh-EPO were already sufficient for the maintenance of the target haematocrit, while in two patients not requiring Rh-EPO treatment an improvement of their moderate anaemia could be observed. These data corroborate the view that calcitriol is an effective drug in secondary hyperparathyroidism. The results suggest that in the improvement of renal anaemia of dialysed patients the reduction of the Se-PTH level also plays a role.
Olfactory dysfunction is one of the main symptoms of Chronic Rhinosinusitis (CRS) caused by bacteria in the form of biofilm. Therapeutic Pulsed Ultrasound (TPU), besides its anti-inflammatory effects has the ability to disintegrate the strong walls of biofilms (community of bacteria), thus help relieve the symptoms of CRS, one of the major symptoms of which is olfactory dysfunction. Case Description: A 42-year-old man with CRS whose olfactory sense had gradually declined over two years, underwent TPU for ten sessions (three days a week) on his maxillary and frontal sinuses. Findings of CT scan and the Sino-Nasal Outcome Test (SNOT-20) questionnaire were employed to assess the severity of the symptoms. Moreover, the Iran Smell Identification Test (Iran-SIT) was used to measure the degree of olfactory dysfunction. Smell dysfunction and the severity of symptom in CRS relatively improved according to SNOT-20 and ISIT scales by 80% and 41%, respectively. It appears that TPU can improve the olfactory dysfunction and other symptoms caused by CRS.
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