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Summary We observed a positive relationship between awareness and educational intervention based on the facts on osteoporosis quiz. There are notable gaps in current nursing knowledge, particularly in terms of preventative strategies. Purpose/Introduction Osteoporosis is one of the main public health concerns and informative health intervention remains important in management of osteoporosis due to modifiable risk factors through non pharmacological approach. The purpose of the survey was to evaluate the awareness and intervention effect on knowledge regarding osteoporosis among nursing professionals. Methods The design of the research investigation was comparative cross-sectional. The Systematic technique was selected for data sampling from 278 nurses using roasoft. Facts on osteoporosis quiz was used for data collection before and after intervention. Health information brochure was used for educating nurses regarding osteoporosis. Results The response rate was 100 percent as all the 278 questionnaires were received back from respondents. Osteoporosis affects both genders was correctly identified by 70.9% nurses before intervention and 82.4% nurses after intervention. There is a weak relationship between bone health (r = 0.35, p = 0.000) strong association between risk factors (r = 0.70, p = 0.000) and treatment and prevention (r = 0.89, p = 0.000). Significant differences were observed by applying paired t-test statistics. Conclusions The findings of the survey concluded a statistically significant association between knowledge and educational intervention. There should be improved teaching in nurses’ syllabi in addition to ongoing nursing instruction programs such as seminars and workshops as deficiency of responsiveness related to osteoporosis was a barrier to adequate patient care.

Summary Introduction: Bauhinia variegata is used in traditional medicine in Pakistan. Objective: The present study was designated to analyze phytochemical screening and cytotoxicity assay of crude aqueous and methanol extracts of flowering buds of Bauhinia variegata. Methods: Qualitative and quantitative phytochemical screening of both extracts were performed by using standard protocols while brine shrimp lethality assay was conducted for cytotoxicity analysis of both extracts. Results: The highest levels of phenolics, flavonoids and terpenoids were observed in methanol extract with respective standard drugs. The aminoacid content was highest followed by phenol and flavonoids in crude aqueous extract of the raw materials. In cytotoxic studies (brine shrimp lethality assay) the use of methanol extract was reported as potent with LD50 of 241.778 µg/ml as compared to aqueous extract with LD50 of 489.7061 µg/ml. Conclusion: This study reveals that the presence of bioactive compounds in both extracts are responsible for the treatment of various ailments and being utilized by the traditional folks as a food as well. And showed that methanol extract possess cytotoxic activity and thus needs further scientific intervention for its value addition.

Background & Objective The risk of adverse reactions necessitated the pharmacovigilance system for patient safety. Literature search documented better health literacy of patients through intervention. This investigation aims to assess the perception and the effect of an intervention on patients regarding adverse reactions caused by drugs.MethodsA pre-diagnostic and post-interventional cross-sectional investigation was designed in hospitals of Islamabad. The proportion of patients was selected based on a stratified probability technique. A prevalidated tool was used to collect the response twice through health promotion brochure with counseling was applied as an intervention.Results The findings of the study disclosed that health intervention improved health literacy among patients. Knowledge of pharmacovigilance was known by 97.9% of the patients in the interventional survey compared to a diagnostic survey in which the majority of the sampled population was not aware. The outcome of intervention on paired variables of knowledge, communication, and practice showed significant differences at the 0.05 level by using t-test statistics.ConclusionThe finding of the investigation provided evidence that patient awareness significantly improved by the health promotion model. Patient participation in the reporting of adverse reactions of drugs will complement the hospital staff reporting. These reports will construct an authentic cross-checked database for rational drug safety practices in Pakistan.