Context The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) provides cancer screening to low income, un- and underinsured women through over 11,000 primary care clinics. The program is well-positioned to work with health systems to implement evidence-based interventions (EBIs) to increase screening among all women. Objective To collect baseline data on EBI use, evaluation of EBIs, and related training needs among NBCCEDP grantees. Design CDC conducted a web-based survey in late 2013 among NBCCEDP grantees for the period July 2012-June 2013. This was the first systematic assessment of EBIs among NBCCEDP grantees. Setting CDC’s National Breast and Cervical Cancer Early Detection Program Participants Primarily program directors/coordinators for all 67 NBCCEDP grantees. Main Outcome Measures Data captured were used to assess implementation of five EBIs, their evaluation, and related training needs. Frequencies and proportions were determined. Cluster analysis identified grantees with similar patterns of EBI use for NBCCEDP clients and providers. Results On average, 4.1 of 5 EBIs were implemented per grantee for NBCCEDP clients and providers. Four clusters were identified including “high overall EBI users,” “high provider EBI users,” “high EBI users with no provider assessment and feedback,” and “high client EBI users.” Only 1.8 EBIs were implemented, on average, with non-NBCCEDP clients and providers. Fewer than half (n= 32, 47.8%) of grantees conducted process or outcome evaluation of one or more EBIs. Overall, 47.6% of grantees reported high or medium training needs for client-oriented EBIs and 54.3% for provider-oriented EBIs. Conclusions NBCCEDP grantees are implementing EBIs extensively with clients and providers. Increased EBI use among non-NBCCEDP clients/providers is needed to extend the NBCCEDP’s reach and impact. Grantee training and technical assistance is necessary across EBIs. Additionally, grantees’ use of process and outcome evaluation of EBI implementation must be increased to inform effective program implementation.