We describe the clinical course of four patients who had Trichosporon mycotoxinivorans recovered from multiple sputum cultures over time with various clinical consequences but no fatalities. We also report successful rapid identification of this organism using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry. CASE REPORTS

Background: Carbon dioxide concentration trending is used in chronic management of children with invasive home mechanical ventilation (HMV) in clinical settings, but options for end-tidal carbon dioxide (EtCO 2 ) monitoring at home are limited.We hypothesized that a palm-sized, portable endotracheal capnograph (PEC) that measures EtCO 2 could be adapted for in-home use in children with HMV. Methods: We evaluated the internal consistency of the PEC by calculating an intraclass correlation coefficient of three back-to-back breaths by children (0-17 years) at baseline health in the clinic. Pearson's correlation was calculated for PEC EtCO 2 values with concurrent mean values of in-clinic EtCO 2 and transcutaneous CO 2 (TCM) capnometers. The Bland-Altman test determined their level of agreement. Qualitative interviews and surveys assessed usability and acceptability by family-caregivers at home. Results: CO 2 values were collected in awake children in varied activity levels and positions (N = 30). The intraclass correlation coefficient for the PEC was 0.95 (p < 0.05). The correlation between the PEC and in-clinic EtCO 2 device was 0.85

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