Aim: In this article we compiled the whole plant of Helicteres.isora Linn showed excellent medicinal merits from ancient time belonging to the family Sterculiacea, which commonly known as murud sheng. Study Design: The Pharmacognostic study i.e. microscopic and macroscopic study with preliminary phytochemical test on different parts of plant performed in a Datta Meghe college of pharmacy,Datta meghe Institute of Medical sciences, Wardha, in collaboration with Balkh university,Mazar-e-Sharif during the period of January 2021 to Septmber 2021. Methodology: In the preliminary study focus on all pharmacognostic, by microscopic identification,by TLC, HPTLC by fingerprint application and phytochemical test of root extract, stem, leaf and fruit powder from different researchers study,  which showed the presence of carbohydrates, protein, alkaloids, cardiac glycoside, flavonoids, tannins, essential oil etc which shows number of medicinal merits Results: During the study all investigators investigate, different region shows minute change in organoleptic charecteristics as well as phytochemical constituents and pharmacological study exhibits activities like Fruit showed Antioxidant, Antidiabetic and Antihyperlipidemic activity, Bark extract showed Antihelmintic activity  , Root extract as  Anticancer. Conclusion: According to study we conclude that  Helicteres Isora Linn whole plant parts as well chemical constituents in every part is effective and used medicinally so further investigations are necessary to find out the active bio active molecules responsible to cure different disorders