Purpose To investigate the changes in kidney elasticity in patients with familial Mediterranean fever using the non‐invasive diagnostic method of shear wave elastography (SWE). Methods The kidney elasticity of 35 FMF patients and 23 healthy control subjects was evaluated with SWE. The relationships were evaluated of the SWE values with eGFR, microproteinuria, FMF severity score, number of attacks per month, and colchicine doses of the FMF patients. Results The kidney stiffness and velocity values of the FMF patients were found to be higher than those of the control group (p < 0.001). A negative correlation was found between the renal stiffness and velocity values and the colchicine dose (r = −0.48, p = 0.004, and r = −0.50, p = 0.003, respectively). Conclusion The results of the current study demonstrated that the SWE values of the FMF patients were significantly higher than those of the control group. SWE can be used as an alternative method in the follow up of FMF patients. In addition, a negative correlation was determined between the colchicine dose and renal stiffness. This suggests that SWE values could be used in the adjustments of colchicine doses. However, there is a need for further studies with greater numbers of patients to support this hypothesis.
Amaç: Çalışmamızda pediatrik yaş grubunda ultrasonografinin apandisit tanısındaki duyarlılığının araştırılması amaçlanmıştır. Gereç Yöntem: Operasyon sonucu apandisit tanısı alan, preoperatif USG tetkiki gerçekleştirilmiş olan ve akut batın nedeni olan ek patolojisi bulunmayan 87 pediatrik olgu çalışmaya dahil edildi. Olguların USG raporları retrospektif olarak incelenerek USG’ nin apandisit tanısındaki duyarlılığı araştırıldı. Ayrıca olguların lökosit sayıları, nötrofil oranları ve CRP değerleri hastane arşivinden ve varsa BT tetkikleri PACS sisteminden incelendi. Bulgular: Olguların %71’i akut apandisit, %29’u perfore apandisitti. Olguların %74’ünün USG’si apandisit ile uyumlu olup USG’nin tanı duyarlılığı %74’dü, %16 olguda USG’de sekonder apandisit bulguları izlenirken %10 olguda USG tetkiki tamamen normaldi. USG ile tanı konulamayan %26 olgudan %10 olgunun tanısı BT ile konulmuş olup %16 olguda tanıya klinik bulgularla gidilmişti. Olguların %62’sinde lökositoz, %84’ünde nötrofil oranında artış (sola kayma), %86’sında ise CRP yüksekliği bulunmaktaydı ve olguların tamamında bu parametrelerin en az biri yüksekti. Sonuç: Ultrasonografi her durumda tanı koymak için yeterli olmasa da çalışmamızda ulaşılan yüksek duyarlılık oranı, ultrasonografinin akut apandisit şüphesi bulunan pediatrik hastalarda ilk seçenek tanı aracı olarak kullanılabileceği bilgisini desteklemektedir.
Splenic artery aneurysm, although rare, is the third most common intraabdominal aneurysm and follows aortic and iliac artery aneurysms. Although the prevalence of splenic artery aneurysm in the general population is not known clearly, studies show that splenic artery aneurysms occur in 1-10% of health individuals and the incidence increases with age. The importance of splenic arteryaneurysm is the potential rupture and life-threatening bleeding risk of 10-25% in non-pregnant patients and up to 70% in pregnancy. There are few reports on the incidence and rupture of splenic artery aneurysms in children. Pediatric arterial aneurysms are rare and underlying processes are frequently associated with liver failure, infection, connective tissue diseases, non-infectious arteritis, and congenital malformations. Early detection of splenic artery aneurysms is important because of the spontaneous rupture and life-threatening bleeding. Splenic artery aneurysms, although rarely seen in pediatric patients, are a serious life-threatening condition in case of rupture and can occurarious reasons. Children with hepatic insufficiency should be monitored closelydue to the possibility of rupture and inability to apply elective treatment methods in case of delay, and it should be kept in mind in the differential diagnosis of hypovolemic children admitted to the emergency department with abdominal pain. Here, a cesepresenting with spontaneous rupture of splenic artery aneurysm and imaging findings and treatment options of splenic artery aneurysm will be discussed.
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