A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Ovaryum ve tuba uterina hastalıkları; over tümörleri; CA-125 antijeni; tümör metastazı; patoloji A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To review the pathological diagnosis of patients underwent laparotomy for adnexal masses accompanied by the literature. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The results of 424 patients from a single center were evaluated. Research criteria include the patient to be of reproductive age or postmenopausal age, CA-125 levels, ascites, bilaterality and whether the pathologic diagnosis of the mass is benign or malignant. R Re es su ul lt ts s: : 200 (47.17%) patients were in the reproductive period, 224 (52.83%) patients were in the postmenopausal period, the average age of the population was 52.65±1.04. Adnexal masses originated from; ovary 385 (90.8%), tuba 22 (5.18%), uterus 3 (0.7%) and distant organs 14 (3.3%). While 18.51% of patients pathologically diagnosed as benign were bilateral, 56.89% of malign patients were bilateral. The presence of the acid was observed in 4.2% of benign patients and in 37.06% of the malign patients. The malignancy was diagnosed in 48 (24%) patients in the reproductive period and 68 (30.35%) patients in the postmenopausal period for laparotomies performed for adnexal masses. The most common benign pathologies in the reproductive period was serous cystadenoma, endometrioma and mucinous cystadenoma, while in the postmenopausal period was serous cystadenoma, mucinous cystadenoma and mature teratoma. The most common malignant pathologic diagnosis in the reproductive period was serous adenocarcinoma, metastatic cancers and endometrioid adenocarcinoma, while in the postmenopausal period was serous adenocarcinoma, mucinous carcinoma and endometrioid adenocarcinoma. Metastatic cancers are more frequent during the reproductive years, the most common benign pathology in both groups was ovarian serous cystadenomas, and malignant pathology in both groups was ovarian serous cystadenocarcinoma. 21 malignant cases (43.75%) in the reproductive period has a CA-125 value higher than 200 mU / ml, while 60 malignant cases (88.20%) in the postmenopausal period has a CA-125 value higher than 35 mU / ml. C Co on nc cl lu us si io on n: : Ovarian pathologies constitute the majority of the adnexal masses. The probability of malignancy increases with advancing age, bilaterality, presence of ascites and high CA-125 values. The frequency of metastatic ovarian cancers in the reproductive period is the characteristic of series.
Langerhans cell histiocytosis (LCH) is a very rare disease of female genital tract, most commonly seen in vulva and unusual in postmenopausal period. Herein, we report the 8th case of pure vulvar LCH in a postmenopausal woman. We pay attention to the differential diagnosis in postmenopausal state, features of pathologic diagnosis, and treatment options.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.