Background The Tzanck smear is a simple, easily applicable, rapid, and inexpensive test
The histopathologic presentation of CL as panniculitis is a very rare and this is the first case of pericarditis after the antimony treatment.
In this study, by addition of dermal fibroblasts to epidermal keratinocytes cultured on the DED, expression of differentiation markers such as keratin 1, keratin 10 and filaggrin was much decreased or absent. These results indicate that dermal fibroblasts controls epidermal morphogenesis in three-dimensional culture models by delaying keratinocyte differentiation. However, further studies are required to evaluate the components of epidermal differentiation by biochemical analysis. References 1 Maas-Szabowski N, Shimotoyodome A, Fusenig NE. Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism. J Cell Sci 1999; 112: 1843-1853. 2 El Ghalbzouri A, Lamme E, Ponec M. Crucial role of fibroblasts in regulating epidermal morphogenesis. Cell Tissue Res 2002; 310: 189-199. 3 Regnier M, Prunieras M, Woodley D. Growth and differentiation of adult human epidermal cells on dermal substrates. Front Matrix Biol 1981; 9: 4-35. 4 Lee DY, Cho KH. The effects of epidermal keratinocytes and dermal fibroblasts on the formation of cutaneous basement membrane in threedimensional culture systems. Arch Dermatol Res 2005; 296: 296-302.
AbstractsConclusions 88 transfers for gastroschisis were conducted over the period. 91% babies were kept within region and transferred within an average time of 80 min in keeping with the network guideline. There have been no patient related clinical incidents. Purpose Antenatally detected urinary tract abnormalities (ADUTA) are increasingly recognized. Our aims were to determine the incidence and outcomes of antenatally diagnosed congenital hydronephrosis in a large cohort. Methods We reviewed the records of 18,853 deliveries between January 2008 and December 2011 at King Abdulaziz University Hospital, Saudi Arabia. ADUTA were recorded and their postnatal medical records were reviewed for demographic and radiological data. Results ADUTA were diagnosed in 327 fetuses (1.7%). The commonest pathology was congenital hydronephrosis (n=313, 95.7%). Cystic renal anomalies were reported in four babies (1.2%) and 10 children (3.1%) were reported to have other renal anomalies, including duplex kidneys or a single kidney. Two-hundred and forty babies with congenital hydronephrosis were followed-up. Hydronephrosis resolved in 99 children (41.2%) within 2 months of birth. Twentynine subjects had underlying renal anomalies (12.1%), including vesico-uretral reflux (n=12, 5%), pelvi-uretric junction obstruction (n=14, 5.8%) and posterior urethral valve (n=3, 1.25%). The best predictor for non-resolving congenital hydronephrosis and underlying anatomical abnormalities was the AP diameter on the first postnatal scan. A cut-off point of 5 mm was found to be 83% sensitive in predicting non-resolving hydronephrosis, while 7 mm was 88% sensitive and 10 mm was 94% sensitive. Conclusion Congenital hydronephrosis is the commonest ADUTA. A large percentage resolved within 2 months of birth, but underlying anatomical abnormalities were found in 12.1%. All babies with antenatally detected hydronephrosis should be examined by US postnatally but further radiological investigations should only be performed for persistent significant AP dilatation ≥10 mm. Backgrounds and aims Pilomatrixoma commonly occurs in children as a single tumor. Multiple tumors are rare. This case report describes the presentation of an 8-year-old girl with multiple pilomatrixomas. Case Report An 8-year-old girl presented with 4 subcutaneous, rock-hard nodules. The average time from the onset of the appearance of other nodules was about 12 months. The sites of occurrence were the right eyebrow, neck, right scapular region, and upper left region of the abdomen. Only the nodule in the abdominal region was 1 cm in diameter, the others were 5 mm in diameter. The nodules were nontender and painless except the 1 in the right scapular region. The overlying skin was normal in appearance, with no evidence of ulceration or discoloration. No concurrent disorders were observed. The preliminary clinical diagnosis was multiple pilomatrixoma. The nodules were tender and painful, and the larger one was surgically excised. Histologically, the nodules consisted of acellular material in ...
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