HighlightsHip dislocation is considered an orthopedic emergency and should be reduced as soon as possible to decrease rate of complications.Bilateral hip dislocation is very rare and usually results from high energy trauma mostly motor vehicle collisions.Asymmetrical bilateral simultaneous hip dislocation with one hip dislocated intra-pelvic through the obturator foramen is rare.Complex dislocation might better be reduced in the theatre.
We found that a fixed combination of perindopril/amlodipine is effective in controlling BP in patients with essential hypertension, with older age, male gender, and diabetes mellitus being independent risk factors for less BP control.
Introduction: Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin molecules, either due to nonsense mutations (premature stop codons) or by large rearrangements (deletions or duplications) that disturb the reading frame and in consequence abolish the production of dystrophin in muscles. Methods: Twenty patients with muscular dystrophy diagnosed by clinical history, family pedigree, CK total and histopathology of muscle biopsy is subjected to screening for all 79 exons of dystrophin gene for deletions and duplications. Results and Discussion: Deletion was detected in 80% of patients, while 15% showed duplication, one patient shows nucleotide substitution (c.10033C>T) in exon 69. Most common deletion found between exon 44 and 52. Conclusion: Our study detected high incidence of gene deletion compared to other studies, the most common deletion is multi exon deletion in the major hot spot of the gene (exon 44-52), also we detected lower incidence of duplication with higher percentage of duplication found distally.
A Published-Ahead-of-Print version of this article was made available online on 30 January 2016. Errors have subsequently been identified in the original publication, and the following corrections should be noted: Section 2.2, 1st sentence, which previously read:Eligibility to participate in the study was based on the diagnosis of essential hypertension in patients 18 years of age or older, with sitting BP levels as follows: systolic blood pressure ( Section 2.6, 2nd sentence, which previously read: BP normalization was defined as SBP \140 mmHg and DBP \90 mmHg in non-diabetic patients without TOD, and SBP \140 mmHg and DBP \85 mmHg in diabetic patients and/or those with TOD.
Should read:BP normalization was defined as SBP B140 mmHg and DBP B90 mmHg in non-diabetic patients without TOD, and SBP B140 mmHg and DBP B85 mmHg in diabetic patients and/or those with TOD.
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