BackgroundInfective endocarditis (IE) is commonly complicated by cerebral embolization and hemorrhage secondary to intracranial mycotic aneurysms (ICMAs). These complications are associated with poor outcome and may require diagnostic and therapeutic plans to be modified. However, routine screening by brain CT and CT angiography (CTA) is not standard practice. We aimed to study the impact of routine cerebral CTA on treatment decisions for patients with IE.MethodsFrom July 2007 to December 2012, we prospectively recruited 81 consecutive patients with definite left-sided IE according to modified Duke’s criteria. All patients had routine brain CTA conducted within one week of admission. All patients with ICMA underwent four-vessel conventional angiography. Invasive treatment was performed for ruptured aneurysms, aneurysms ≥5 mm, and persistent aneurysms despite appropriate therapy. Surgical clipping was performed for leaking aneurysms if not amenable to intervention. Results: The mean age was 30.43±8.8 years and 60.5% were males. Staph aureus was the most common organism (32.3%). Among the patients, 37% had underlying rheumatic heart disease, 26% had prosthetic valves, 23.5% developed IE on top of a structurally normal heart and 8.6% had underlying congenital heart disease. Brain CT/CTA revealed that 51 patients had evidence of cerebral embolization, of them 17 were clinically silent. Twenty-six patients (32%) had ICMA, of whom 15 were clinically silent. Among the patients with ICMAs, 11 underwent endovascular treatment and 2 underwent neurovascular surgery. The brain CTA findings prompted different treatment choices in 21 patients (25.6%). The choices were aneurysm treatment before cardiac surgery rather than at follow-up, valve replacement by biological valve instead of mechanical valve, and withholding anticoagulation in patients with prosthetic valve endocarditis for fear of aneurysm rupture.ConclusionsRoutine brain CT/CTA resulted in changes in the treatment plan in a significant proportion of patients with IE, even those without clinically evident neurological disease. Routine brain CT/CTA may be indicated in all hospitalized patients with IE.

Background and objectivesSurgical procedures such as laparoscopic and robotic surgeries are popular since they are invasive in nature and use miniaturized surgical instruments for small incisions. Tracking of the instruments (graspers, needle drivers) and field of view from the stereoscopic camera during surgery could further help the surgeons to remain focussed and reduce the probability of committing any mistakes. Tracking is usually preferred in computerized video surveillance, traffic monitoring, military surveillance system, and vehicle navigation. Despite the numerous efforts over the last few years, object tracking still remains an open research problem, mainly due to motion blur, image noise, lack of image texture, and occlusion. Most of the existing object tracking methods are time-consuming and less accurate when the input video contains high volume of information and more number of instruments. MethodsThis paper presents a variational framework to track the motion of moving objects in surgery videos. The key contributions are as follows: (1) A denoising method using stochastic resonance in maximal overlap discrete wavelet transform is proposed and (2) a robust energy functional based on Bhattacharyya coefficient to match the target region in the first frame of the input sequence with the subsequent frames using a similarity metric is developed. A modified affine transformation-based registration is used to estimate the motion of the features following an active contour-based segmentation method to converge the contour resulted from the registration process. Results and conclusionThe proposed method has been implemented on publicly available databases; the results are found satisfactory. Overlap index (OI) is used to evaluate the tracking performance, and the maximum OI is found to be 76% and 88% on private data and public data sequences.

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Atraumatic convexity subarachnoid hemorrhage (cSAH) is a rare non‐aneurysmal SAH, commonly due to ipsilateral internal carotid artery (ICA) stenosis. It is unusual for the cSAH to occur contralaterally to the infarct. We report two cases of acute ischemic stroke associated with contralateral and ipsilateral cSAH that had different presentations.