Introduction: The primary aim of this study is to evaluate the effect of anesthesia methods on in-hospital, 30-day, and six-month mortality following geriatric hip fracture surgery. The secondary aim is to evaluate the effect of preoperative comorbidities on mortality. Method: This retrospective study included patients aged ≥75 years who had undergone femoral neck fracture surgery. Results: The data of 135 patients were analyzed. The postoperative stay in the intensive care unit of patients who were given general anesthesia (p < 0.05) was significantly longer. In the comparisons made according to survival, the exitus cases were found to have higher rates of renal disease and dementia. The variables found to be significantly different in the paired comparisons and determined to be a risk factor as a result of logistic regression analysis were applied with an receiver operating characteristic analysis, as a result of which a cutoff value of 6 in the modified Charlson comorbidity index score was found to be statistically significant area under curve = 0.727, p < 0.001, 95% CI: 0.644–0.800). The cutoff value for preoperative hemoglobin was determined to be 11.4 (Area under curve = 0.643, p = 0.005, 95% confidence interval: 0.556– 0.723). Conclusions: Ensuring the preoperative waiting time does not exceed 48 hours, optimizing the medical and hemodynamic status with a multidisciplinary approach, and determining the anesthesia method according to the clinical characteristics of each patient may contribute to reducing mortality rates. Keywords: Hip Fractures; Geriatrics; Anesthesia; Mortality.

Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disease, which may be accompanied by scoliosis, cardiac, endocrine and pulmonary comorbidities. We present our anesthesia experiences using total intravenous anesthesia (TIVA) method in scoliosis surgery of four patients with Friedreich ataxia. Patients were monitored with central venous pressure (CVP), bispectral index (BIS),invasive blood pressure and near infrared spectroscopy (NIRS). The risk of malignant hyperthermia and difficult airway are increased in patients with Friedreich's ataxia. We were prepared for difficult airway and provided dantrolene preoperatively. Neuromuscular blocker was used for anesthesia induction in one case, we did not use it in the other cases. Hypertrophic cardiomyopathy may accompany patients with Friedreich's ataxia. Therefore, detailed preoperative examination, intraoperative close bleeding, blood gas analysis, hemodynamic monitoring and postoperative multimodal analgesia for hemodynamic stability in patients with Friedreich's ataxia were performed. We aimed to discuss our anesthesia management with four patients with Friedreich's ataxia who underwent scoliosis surgery.

ABSTRACT Objective: Ischemic complications or massive bleeding are important perioperative complications in elderly patients using antithrombotic drugs. The need for blood product replacement, transfusion-related complications, prolonged stay in hospital and intensive care unit, and high mortality in the perioperative period can be seen. The aim of this study was to investigate the effects of long-term different antithrombotic therapies on morbidity and mortality in elderly patients undergoing surgery for hip fracture. Materials and Methods: This retrospective cohort study included patients aged 65 years and older who underwent surgery for hip fracture between 2015 and 2018. Patients with no antithrombotic treatment (Group NonAT), warfarin (Group Warfarin), novel oral anticoagulants (Group NOACs), or dual antiplatelet therapy (Group DAPT) were compared in terms of major bleeding, deep venous thrombosis (DVT) and pulmonary thromboembolism (PTE) complications, length of hospital stay (LOS), ICU admission, and 30-day mortality. Results: The study included 668 patients; demographic data in Group NonAT (n=442), Group Warfarin (n=59), Group NOACs (n=30) and Group DAPT(n=137) were similar. Major bleeding and red blood cell transfusion did not differ statistically between all groups. (p>0.05) The preoperative and postoperative Hb values of the patients were not statistically different between the groups (p>0.05). Mortality, only there was statistically significantly higher in the dual antiplatelet group than the non user group. (p0.05) However survival was statistically significant different (p