Loss of posterior teeth impacts a patient’s function as well as their facial esthetics. Changes in the Occlusal Vertical Dimension (OVD) may result in anterior crossbite or Class III malocclusion. This clinical report describes the prosthodontic management and stabilization of a patient with reverse anterior articulation due to loss of posterior occlusal support.The comprehensive diagnostic approach,the information gathered from the provisional phase and the consistent sequence of clinical and laboratory stages led to a definitive treatment outcome that guaranteed the success of the prostheses and the patient’s comfort and satisfaction.The clinical case described indicates that the prosthodontic management of Class III malocclusion, when carefully planned, can be a safe procedure that aims to ensure the immediate and longitudinal improvement of a patient’s function and esthetics.The treatment was based on the class III diagnosis. Therefore, the patient was rehabilitated by occlusal adjustments and conventional teeth and tissue - supported prostheses and without the need for invasive orthognathic surgery.