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Questioning of comorbid OCS and treatment with specific medication in schizophrenia patients may increase QoL.

Most of the involuntarily hospitalized psychiatric inpatients were male, were not working and had the diagnosis of schizophrenia. These general psychiatric risk factors were more important in involuntary hospitalization compared to voluntary hospitalization. We concluded that the high prevalence of involuntary hospitalizations deserved further studies.

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Objective: The usage of synthetic cannabinoids (SCs) has increased both in Turkey and all worldwide. Here, we evaluate if SCs cause ventricular repolarization abnormalities using initial and after 12th-hour electrocardiograms in patients with acute intoxication of SCs. We examined changes in the QTc and cTp-e parameters to demonstrate ventricular repolarization effects of the usage of SCs. Material and Methods: We used a prospective study design. Twenty patients were included who visited the emergency department, complaining of clouding of consciousness after using SCs. The QT, QTc and Tp-e intervals and several other electrocardiographic parameters were measured at baseline and 12 hours after the usage of SCs. Results: The QRS duration was significantly decreased (102.1 ± 15.5 ms vs 95.0 ± 10.7 ms; p = 0.022). We noted a significant decrease in cQT measurements at the end of the 12th hour (426.6 ± 47.2 ms vs 390.4 ± 42.9 ms; p = 0.002). Similarly, the Tp-e and cTp-e values decreased significantly when SCs lost its acute effect (93.4 ± 21.1 ms vs 77.4 ± 21.0 ms; p = 0.014, 105.3 ± 28.5 ms vs 88.1 ± 21.5 ms; p = 0.01). Conclusions: The usage of SCs affects ventricular repolarization heterogeneity based on QTc and Tp-e intervals