This study investigates nutritional value, amino acid profile, and total anthocyanin in pigmented rice as an antioxidant and anti-diabetic agent. Six rice varieties were extracted using 0.1% HCl in methanol, namely four red rice, one black rice, and one white rice. Rice extract was used for proximate analysis and amino acid profiling. Total anthocyanin was measured and identified by ultraviolet-visible (UV-Vis) spectrophotometer and thin-layer chromatography (TLC). The antioxidant activity was determined using Ferric-reducing antioxidant power (FRAP) assay, and the α-amylase enzyme-inhibited by anthocyanin extract of red rice as anti-diabetic was measured. The study result showed that the proximate level (carbohydrate, protein, lipid, water, and ash) in pigmented rice was different. Cempo merah red rice is a source of amino acids, both essential and non-essential amino acids that act as good nutrition. The highest total anthocyanin level between red rice varieties of 10.87 mg/g was found in Aek sibundong red rice. High biological function activities as an antioxidant were indicated by Aek sibundong red rice with an IC50 value of 6.65 µg/mL. Aek sibundong red rice shows the lowest IC50 value of 144.46 µg/mL in anti-diabetic activity. Thus, Aek sibundong red rice may have the potential as α-amylase inhibitor for diabetes prevention.
Individual fitness levels can affect team performance. The problem of this study is to describe the fitness level of male basketball players at Negeri Semarang University. A total of 19 male athletes participated in this study. A descriptive quantitative method with sport-specific tests and measurements was used in this study. His average BMI is 2.52. Average agility he is 12.92 seconds. His average balance is 9.03 seconds. Average aerobic endurance is 39.20 ml/kg/min. His average arm strength is 33.94. The average abdominal muscle strength is 26.52 times. The average explosive force is 58.57cm. Flexibility averages him 15.78 cm, and eye-hand coordination averages 17.68 catches. As a result, male basketball players at Negeri Semarang University reported an average of 55.7% of their fitness levels.
Tujuan dari penelitian ini adalah untuk menganalisis pertandingan final NBA musim 2020-2021 antara Milwaukee Bucks melawan Phoenix Suns berdasarkan statistik pertandingan. Dibutuhkan 6 pertandingan sampai akhirnya Milwaukee Bucks dinobatkan menjadi juara NBA dengan 4 kali menang dan 2 kali kalah dari Phoenix Suns. Penelitian ini menggunakan metode deskriptif kuantitatif. Data yang digunakan menggunakan data sekunder yang diambil dari website resmi NBA. Hasil penelitian menunjukkan bahwa: 1) faktor penentu kemenangan Phoenix Suns dalam pertandingan pertama adalah FTM dan FT%. Faktor kekalahan Milwaukee Bucks adalah pada FTM dan FT%, 2) Faktor penentu kemenangan Phoenix Suns dalam pertandingan kedua adalah 3PM, 3P%, dan DRB. Faktor kekalahan Milwaukee Bucks adalah 3PM, 3) Milwaukee Bucks mendominasi pertandingan ketiga dengan unggul dalam 9 komponen statistik, khususnya dalam 3PM dan 3P, 4) Faktor penentu kemenangan Milwaukee Bucks pada pertandingan keempat adalah FTM dan ORB. Faktor kekalahan Phoenix Suns adalah FTM yang rendah, 5) Faktor yang mempengaruhi kemenangan Milwaukee Bucks pada pertandingan kelima adalah 3PM, AST, dan ORB. Faktor kekalahan Phoenix Suns adalah tidak memaksimalkan 3P% yang cukup tinggi yaitu 68,3% dan FT% yaitu 90,9% dengan memperbanyak percobaan tembakan, 6) Faktor yang mempengaruhi kemenangan Milwaukee Bucks pada pertandingan keenam adalah FG%, FTM, FT%, AST, ORB, dan DRB. Faktor kekalahan Phoenix Suns adalah FTM dan rebounds yang kurang baik.
Dengue fever is an infectious disease caused by the dengue virus, and there is no yet effective drug to treat this disease successfully. Our study aimed to identify the bioactive compounds of Acorus calamus L. and its potential role in inhibiting dengue virus NS3 protease-helicase. Liquid Chromatography-Mass Spectrometry analyzed phytochemical constituents. Drug-likeness of the predominant compound methanol extract of Acorus calamus L. was investigated through the SWISS ADME server. Complex molecular interactions were investigated by Hex 8.0 docking program and Discovery studio 2016. Our study revealed that the five largest phytochemicals in the extract were acoric acid, acorone, acoradin, acoronene, and calamendiol. All predominant compounds are potent to be developed as drug candidates. Molecular docking results showed that the five compounds bind to the Arg599, Pro291, Lys388, Pro431, and His487 of the dengue virus NS3 protease-helicase, the ligand-binding site that plays an essential role in viral replication. The ligand-protein binding pattern exhibited hydrogen and hydrophobic interactions. The interaction of the acoradin-NS3 protease-helicase complex had the lowest binding energy of -299.7 kcal/mol. In summary, we conclude that Acorus calamus L. extract may have prospects as a drug for dengue virus infection.
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