Globally it is stated that the consumption of alcohol has increased all over the world in the past decade. About 3.3 million deaths, or 5.9% of all global deaths, were attributable to alcohol consumption. Uganda was reported to have one of the highest levels of alcohol consumption in East Africa region. This study aimed at assessing “Knowledge and Practice on alcohol consumption among youth in Kizinda town Bushenyi district. A cross-sectional study design was used, target population were youth of age 15-30 years irrespective of sex. A sample size of 109 participants was used and data was obtained by using questionnaires, data entered into SPSS, analyzed and presented inform of pie charts, tables and graphs. 69(63.3%) of the respondents had faced problems as a result of alcohol, 77(70.6%) knew that alcohol consumption was associated with serious health and social consequences. 50(45.9%) said was associated with motor vehicle accident. Majority took Beers, larger or stout 39(35.8%), 49(45.0%) took alcohol with additives and soda 19(38.8%) as most used additive for reasons of favoring strong drink 20(40.8%). This study revealed that alcohol consumption was harmful and many got information on effects of alcohol from friends and classmates. Alcohol consumption was seen to be associated with motor vehicle accidents. Beers, lager or stout were the most taken. Keywords: Alcohol, Beers, Youths, Kizinda Town.