Abstract-The paper deals with simulation of in-situ uranium leaching technological process, collecting data for forecasting and leaching process control. It provides numerical simulation of uranium in-situ leaching (ISL) using Comsol Multiphysics software package application.Previous studies evaluated main hydrodynamic characteristics of wells and reservoirs, such as the coefficient of resistance and the saturation recovery; while this paper is concerned with determining the changes in process variables in the wells during operation.