This study was conducted to investigate if silymarin can prevent the adverse effect of oxidative stress induced by carbon tetrachloride(CCl4) on some characters of male rat reproductive system. Twenty male albino rats were divided into 4 groups, 5 for each included, control group, CCl4 group, silymarin group and silymarin plus CCl4 group. Groups with silymarin received dose (150mg/kg) and group with CCl4 received (3ml/kg) at the end of experiment. The period of the study was 35 days. CCl4 can induce male reproductive toxicity through damage testis structure, weights, reduction in epididymis, sperm count, morphology, viability and motility. Silymarin plays its antioxidant role with scavenging free radical resulted by CCl4 and showed significant increasing in body and testis weight, normal sperms counting and vital sperms in compared to CCl4 group.

This study was conducted to investigate if silymarin can prevent the adverse effect of oxidative stress induced by carbon tetrachloride(CCl4) on some characters of male rat reproductive system. Twenty male albino rats were divided into 4 groups, 5 for each included, control group, CCl4 group, silymarin group and silymarin plus CCl4 group. Groups with silymarin  received dose (150mg/kg) and group with CCl4 received (3ml/kg) at the end of experiment. The period of the study was 35 days. CCl4 can induce male reproductive toxicity through damage testis structure, weights, reduction in epididymis, sperm count, morphology, viability and motility. Silymarin plays its antioxidant role with scavenging free radical resulted by CCl4 and showed significant increasing in body and testis weight, normal sperms counting and vital sperms in compared to CCl4 group.

The study include effect therapeutic dose of metformin drug in blood sugar of pregnant mice treated with folic acid. Mice weight ranged (25±2) g with age (12-16)weeks ,The concentrations of uesd were (0.18 & 0.53) mg \ 25 gm mice body weight which corresponded to (500&1500) mg\70 Kg of body weight in adult human , The therapeutic dose of folic acid used was (0.002) mg\mice body weight which corresponded to (5) mg \ body weight in human , was aimed to define the effects of drugs in sugar level during pregnancy with the presence of folic acid or its absence , The drug was orally administrated , at (6-18) th day of pregnancy while folic acid was administrated at (4-18) th day. This group was treated with metformin drug after 2 hours of folic acid admimstration at (6) th day , The administration was once in the morning of each , The results showed non significant decrease in the sugar level in groups treated with metformin while significant increase in groups treated with metformin drug and folic acid compared with control.

This study was designed to impact the effect of fenugreek (Trigonella foenum-graecum), sesame (sesamum indicum), and domperidone on the mammary glands of pregnant white rats spices Rattus norvegicus at different concentrations. Fenugreek was used in an oral dose of 0.5 ml / day as oil, while sesame was used with a dose of 1 g / day as powder and domperidone was used as liquid as an oral dose of 2 mg / day . The results of the histological examination in the group that dosed the fenugreek showed an increase in the size of the lobules and alveoli, and the lumen was larger than the control group, as well as its branching. The cavities contain internal folds representing the branching of the vesicle wall and the increase of the secreted material in addition to containing an amount of fat in the form of fat droplet within the secretory materials in the lumen Alveoli. In the group dosed with sesame observed an increase in the size of lobules and alveolitis and their branching and increased secretory material compared with the control group was also found, but that was less than the other two test groups. In the domperidone group was found an increase in the size of lobules and alveoli and an increase in branching was observed. The secreted material inside the alveolar cavities also increased with an increase in lipid droplets within the secretory material compared with the control group and the other two experimental groups