Ten pituitary giants have been seen in hospitals in the Manchester region between 1938 and 1980, nine of whom are still alive. We report the clinical and hormonal features in eight of these cases. Marked skeletal deformity and C .-

Summary Two patients with Behçet’s syndrome are described. One patient developed spontaneous bilateral popliteal artery aneurysms and the other spontaneous thrombosis of the superior vena cava. These cases emphasize that primary inflammatory lesions of large vessels, with arterial aneurysm formation and thrombosis may be a feature of the syndrome.