Alkaloids U 0600Pyrrolizidine Alkaloid Containing Plants Used in Mongolian Traditional Medicine: Lappula myosotis Moench. -From the ethanol extract of the title plant lycopsamine (Ia), intermedine (Ic) and the corresponding acetyl derivatives (Ib) and (Id) are isolated. -(WIEDENFELD*, H.; AMARSANAA, B.; ALTANCHIMEG, D.; NARANTUYA, S.; Sci. Pharm. 73 (2005) 3, 139-145; Inst. Pharm., Rhein.
Lappula myosotis Moench. (Boraginaceae) is a plant growing wide-spread in the Mongolian Aimags Khubsgul, Khangai, Khentei, Mongol dahurica, Altai and Alasha Gobi [1]. From this plant four pyrrolizidine alkloids were isolated and their structures determined using spectroscopical methods: lycopsamine, intermedine and their acetylderivatives. This plant is used in the Mongolian traditional medicine externally but on account of its high level of alkaloids (~ 0.2%) the usage of L. myosotis may be hazardous for humans.
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