This is comprehensive study of malaria and malaria infection in Gusau Township to generate baseline line information which may be useful in the planning control and preventive measures. A total of 5666 blood samples from patients were examined for malaria parasites between the month January to December, 2017, out which 2606 representing 46.0% were positive for malaria parasites, which was high. Both males and females were equally infected at the same rates and between the age groups. Malaria was hyperendemic in Gusau Township with transmission occurring throughout the months of the year. The best way to prevent malaria is avoiding mosquito bite through the use mosquito nets and screening of windows and doors.