A study to determine the optimum tilt angle for installing photovoltaic solar panels in Zomba district, Malawi, has been conducted. The study determined the optimum monthly tilt angles of PV solar panels and the seasonal adjustments needed for the panels in order to collect maximum solar radiation throughout the year. In this study, global solar radiation (GSR) on four tilted surfaces was measured. The north-facing surfaces were titled at angles of 0°, 15°, 20°, and 25°. The GSR data was used to determine the daily and monthly optimum tilt angles for the PV panels. The optimum tilt angles were found to be 0° or 25° depending on the time of the year. From October to February, the optimum tilt angle has been determined to be 0° and, from March to September, the optimum tilt angle is observed to be 25°. There are only two seasonal adjustments that are needed for PV solar panels in Zomba district and these should be carried out at the end of February and at the end of September. For fixed solar panels with no seasonal adjustments, the optimum tilt angle for the PV solar panels that are northfacing has been determined to be 25°.