Although the application of electrical neuromodulation has yielded promising results, further studies such as optimising the operational parameters are necessary. Due to the fact that most commercially available stimulators are not suitable for animal experiments in terms of size, weight and structure, a programmable and implantable neurostimulator for treating chronic disorders in freely behaving small animals is developed in this reported study. This stimulator was compatible with different applications with reserved ports and software updating. The stimulator exhibited good performance and provided a platform for animal study on electrical stimulation therapy.

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