Long-term changes in the plant biomass of the dried bottom of the Aral Sea and the Karakalpak part of the Ustyurt plateau were determined. Despite the drying of the Aral Sea 50 years ago, primary and intermediate stages of vegetation haloseries dominated by annual and shrub halophyte fraction remains as the main directing force of succession. The emergence and increase in the area of "zero" or arid local territories after the 1990s is observed in the central, especially southern part of the Karakalpak Ustyurt. In contrast to the formation of vegetation on the drained bottom of the Aral Sea, long-term changes in the biomass of various natural-territorial complexes of Ustyurt are characterized by a negative correlation with a reduction in the area of mirrors over the past 30 years.