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Recebido em 29/9/09; aceito em 22/3/10; publicado na web em 30/7/10Cefdinir has broad spectrum of activity and high prescription rates, hence its counterfeiting seems imminent. We have proposed a simple, fast, selective and non-extractive spectrophotometric method for the content assay of cefdinir in formulations. The method is based on complexation of cefdinir and Fe under reducing condition in a buffered medium (pH 11) to form a magenta colored donoracceptor complex (l max = 550 nm; apparent molar absorptivity = 3720 L mol -1 cm -1). No other cephalosporins, penicillins and common excipients interfere under the test conditions. The Beer's law is followed in the concentration range 8-160 µg mL -1 .

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