Bizzare parosteal osteochondromatous proliferation, or Nora‘s lesion is a unique bone lesion that most often arises in the small bones of hands and feet. It is characterised by proliferation of chondroid, bony and fibrous tissue, and is occasionally misdiagnosed as a malignant process. Our case was a 31 yr old lady, who presented with a painless swelling near the 5th metacarpal bone of right hand. X-ray showed well marginated mineralised mass arising from the cortical surface of the metacarpal bone. Histopathological examination revealed bizarre parosteal osteochondromatous proliferation composed of varying amounts of cartilage, bone and spindle cells. Cartilage was hypercellular and chondrocytes were enlarged. Ossification was irregular and had a peculiar blue tinctorial quality.
The most frequently occurring retroperitoneal tumors are those of the kidneys, adrenal glands, and the pancreas. A primary retroperitoneal tumor composed of granulosa cells and developing far away from the normal location of the ovary is less frequently observed. A 69-year-old female patient presented with abdominal discomfort. Computerized tomography (CT) of the abdomen revealed a solid heterogeneous mass lesion measuring 11.2 cm × 8 cm × 12 cm consistent with retroperitoneal hematoma. Ultrasonography (USG)-guided aspiration smears revealed cytological features suggestive of adult-type granulosa cell tumor (AGCT). As the patient had a history of hysterectomy with bilateral salpingo-oophorectomy 22 years ago for leiomyoma, a diagnosis of extraovarian AGCT was made. Intraoperatively, the tumor was removed in piecemeal that showed yellowish areas with extensive necrosis and hemorrhage. Histopathological examination of the excised mass and inhibin positivity confirmed the diagnosis. Primary retroperitoneal extraovarian GCT is a rare tumor with only 12 cases reported in medical literature in English.
Entomophoromycosis is a rare mycotic infection affecting the subcutaneous tissue and nasal mucosa. Entomophthorales are seen in immunocompetent individuals. We present the case of a 22-year-old man who presented with nasal obstruction, unilateral watering from eye, and oral mass. On examination, the patient had an oronasal mass completely filling the left nasal cavity and extending into the left oropharynx. He also had left nasolacrimal duct obstruction. The mass was excised by a combined endoscopic and transoral microscopic approach along with endoscopic dacryocystorhinostomy. Postoperative biopsy was entomophthoromycosis. The patient was put on itraconazole and is on follow-up. This case is unique because of its atypical presentation. We also discuss the nuances regarding its optimal management as per the available literature and how we successfully managed the case.
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