The main aim of the present study is to collect information and identify the specimens of ethnobotanical plants used for the treatment of diarrhoeal disease by the Mishing people of Dhemaji and Lakhimpur districts, Assam. From the Dhemaji district, we have selected Jonai, Silapathar, Sissikalghar, Dhakuakhana, and Boginodi, which are selected under the Lakhimpur district purposefully. Information was collected from randomly selected households, both male and female respondents, and different age groups between 45-85 years of age. An investigation of a total of 66 plant species and 39 families was enumerated, and Rutaceae, Apiaceae, Zingiberaceae, Clusiaceae, Moraceae, and Combretaceae were the dominant families.