Muscles are the only tissue in the body that has the ability to contract and therefore move the other parts of the body. Physical activity is the one important factor which affects the skeletal muscle function. Regular physical activity is recommended in youth today to improve the physical and mental well being. The aim of this study is to assess the skeletal muscle function in sedentary and physically active young adults by using Mosso's ergogaph and 40mm endurance test. A cross sectional study was conducted among 50 sedentary and 50 physically active healthy medical and paramedical students in the