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Introduction: Ectopic opening of the common bile duct (EO-CBD) is a rare pathology, and its management is important. To date, only a few studies have been conducted for EO-CBD due to its low incidence. Materials and Methods:A retrospective review was conducted on 54 patients with available prospective data. Among them, 30 patients (group 1) underwent choledochoduodenostomy for reasons other than anomalous opening, and 24 patients (group 2) had an EO-CBD.Results: Endoscopic retrograde cholangiopancreatography (ERCP) was performed for 24 patients with duodenal deformity and apical stenosis. EO-CBD was detected in 2.72% of all patients who underwent ERCP (24/880 ERCPs). The occurrence of hyperbilirubinemia (total bilirubin > 1.2 mg/dL) was not significantly different between groups: 3.83 ± 4.57 mg/dL for group 1 and 2.26 ± 2.17 mg/dL for group 2.Conclusions: Failed ERCP, giant stones, and recurrent episodes ( > 2) of cholangitis requiring ERCP constitute indications for surgical treatment in cases of EO-CBD into the duodenum.

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Cite this article as: Muhammedoğlu B. Single-stage treatment with ERCP and laparoscopic cholecystectomy versus two-stage treatment with ERCP followed by laparoscopic cholecystectomy within 6 to 8 weeks: A retrospective study.

We would like to thank you for the opportunity to respond to the issues raised by the author of the "Letter to the Editor" and to clarify aspects of statistical methodology and certain points for our article published in the latest issue of the Surg Laparosc Endosc Percutan Tech in relation to these concerns. We would also like to thank our colleague for his interest in our paper and for taking the time to express his concerns.The paper contains a lot of data. In Reply to the Letter, we would like to discuss some points in this letter. The percentages in the quoted sentences are data taken from published articles. As stated in the Conclusions section, our study supports combined treatment methods. In our paper, combined preoperative and postoperative approaches for liver hydatid disease along with a schematic representation of practical suggestions are presented. We believe that a valuable and unique approach was proposed in a diagram for the physician following the patient.In our study, surgical treatment was performed for all patients, but only patients with appropriate indications underwent endoscopic retrograde cholangiopancreatography. All patients were administered adjuvant and neoadjuvant antihelminthic therapies. The number