Abundant Early Cretaceous magmatism is conserved in the central and southern Great Xing’an Range (GXR) and has significant geodynamic implications for the study of the Late Mesozoic tectonic framework of northeast China. In this study, we provide new high-precision U–Pb zircon geochronology, whole-rock geochemistry, and zircon Hf isotopic data for representative intrusive rocks from the northern part of the Ulanhot area to illustrate the petrogenesis types and magma source of these rocks and evaluate the tectonic setting of the central-southern GXR. Laser ablation inductively coupled plasma–mass spectrometry (LA-ICP-MS) zircon U–Pb dating showed that magmatism in the Ulanhot area (monzonite porphyry: 128.07 ± 0.62 Ma, quartz monzonite porphyry: 127.47 ± 0.36, quartz porphyry: 124.85 ± 0.34, and granite porphyry: 124.15 ± 0.31 Ma) occurred during the Early Cretaceous. Geochemically, monzonite porphyry belongs to the metaluminous and alkaline series rocks and is characterized by high Al2O3 (average 17.74 wt.%) and TiO2 (average 0.88 wt.%) and low Ni (average 4.63 ppm), Cr (average 6.69 ppm), Mg# (average 31.11), Y (average 15.16 ppm), and Yb (average 1.62 ppm) content with enrichment in Ba, K, Pb, Sr, Zr, and Hf and depletion in Ti, Nb, and Ta. The granitic rocks (e.g., quartz monzonite porphyry, quartz porphyry, and granite porphyry) pertain to the category of high-K calc-alkaline rocks and are characterized by high SiO2 content (>66 wt.%) and low MgO (average 0.69 wt.%), Mg# (average 31.49 ppm), Ni (average 2.78 ppm), and Cr (average 8.10 ppm) content, showing an affinity to I-type granite accompanied by Nb, Ta, P, and Ti depletion and negative Eu anomalies (δEu = 0.57–0.96; average 0.82). The Hf isotopic data suggest that these rocks were the product of the partial melting of juvenile crustal rocks. Notably, fractionation crystallization plays a crucial role in the process of magma emplacement. Combining our study with published ones, we proposed that the Early Cretaceous intrusive rocks in the Ulanhot area were formed in an extensional tectonic background and compactly related to the subduction of the Paleo-Pacific Ocean plate.