The seriousness of pancreatic diseases and the utmost importance of its correct diagnosis and treatment are expected to be helpful in correlating the functional capacity for further study in basic science and in decision making in clinical settings especially in transplant surgery of pancreas. Knowledge of normal morphometry of pancreas in living subjects is essential for understanding the segmental resection of pancreas as well as pancreatic imaging. A descriptive and cross-sectional study was conducted in the Department of Anatomy, Forensic Medicine & Pathology of Gauhati Medical College, Guwahati from May, 2016 to December 2019 on 103 specimens of human pancreas from 13 to 78 years age of both sexes. The collected samples were divided into seven age groups: A (10-19 years), B (20-29 years), C (30-39 years), D (40-49 years), E (50-59 years), F (60-69 years) and G (≥70 years), for convenient description. The differences between length of pancreas were statistically significant in A vs C, A vs D, A vs E, A vs F, A vs G, B vs C, B vs D, B vs E, B vs F and B vs G. The differences between weight of pancreas were statistically significant in A vs F, B vs C, B vs G, C vs D, C vs F, D vs F, E vs F, E vs G and F vs G. The present study is expected to standardize the morphology of pancreas in Assamese population.

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INTRODUCTION: The islets of Langerhans may contain a few cells or many hundreds of polygonal cells arranged in short irregular cords that are abundantly invested with a network of fenestrated capillaries to produce a hormone with glucose-lowering effect. MATERIALS AND METHODS: The descriptive and cross-sectional study was done in the Department of Anatomy, Forensic Medicine& Pathology of Gauhati Medical College, Guwahati based on collection of 103 human pancreas aging from 13 to 78 years of both sexes.The collected samples were divided into group A (10-19 years),B (20-29 years),C (30-39 years),D (40-49 years),E (50-59 years),F (60-69 years) and G (≥70 years).Measurement of five slides selected from head, body and tail region were examined under 400 magnification. RESULTS AND OBSERVATION:The differences between the diameter of pancreatic islets for head part were statistically significant in A vs B,A vs D,A vs E,A vs F,A vs G,B vs D,B vs E,B vs F,B vs G, C vs E,C vs F,C vs G,F vs G in body part A vs B,A vs C,A vs F, A vs G,B vs C,B vs D,B vs E,B vs F,B vs G,C vs G,D vs G,E vs G and F vs G.and in tail part between A vs B,A vs C,A vs D,A vs E, A vs F, A vs G, B vs C, B vs D, B vs E, B vs G, C vs E, C vs F, C vs G, D vs F, D vs G, E vs F , E vs G and F vs G region. CONCLUSIONS:In the 3 region it was found that in the both extremities of life the diameter of islets of Langerhans was gradually decreased as age increases. Larger samples and advanced procedures in case of normal and abnormal population like people with diabetes disease for further studies may recommended.