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Tryptase is a serin-protease produced and released by mast cells after IgE-mediated or non-IgE mediated stimuli. We here review the various aspects related to the molecular characteristics of the enzyme and its biological effects, the genetic basis of its production and the release kinetics. Recommendations for the clinical use of tryptase measurement developed by a task force of

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This article has been accepted for publication and undergone full peer review but has not been through the copyediting, types etting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as

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