Brainstem tumors are rare pathologies, brainstem glioblastoma is even rarer. We report three pediatric patients who underwent subtotal tumor resection for brainstem tumors diagnosed as brainstem glioblastoma. The clinical courses and treatment procedures were discussed alongside a comprehensive literature review. Treatment of brainstem high-grade gliomas includes steroids, surgery, radiotherapy, and chemotherapy. However, none of these treatment modalities effectively prolongs survival time. According to literature, the median overall survival of these patients are approximately between 9 to 12 months. Glioblastoma has a poor prognosis in pediatric patients with high-grade brainstem gliomas. Radiotherapy is associated with a decreased risk of mortality at 9 months but not long-term.

ÖZETTiroid kanserleri yıllık endokrin organlara ait kanser ölümlerinin çoğundan sorumludur (1,2) . Bu tümörlerin % 90'ı folliküler hücrelerden köken alırken, geri kalanı kalsitonin üreten C hücreleri veya diğer hücre tiplerinden kaynaklanmıştır. Diferansiye (papiller ve folliküler) tiroid kanserleri yavaş ilerler ve sağ kalımları uzundur. Anaplastik tiroid kanserleri ise tüm insan kanserlerinin en agresif olanı olup, çoğu olguda survi 1 yıldan azdır, ancak ender görü-lür. Kötü diferansiye tiroid kanserleri az anlaşılmış tümör grubu olup, 5 yıllık survi yaklaşık