Background: Breast cancer is the most common cancer among Iranian women. Since development of the disease in Iranian women occurs relatively early, the survival rate matters considerably. In different countries, survival of breast cancer patients varies considerably. Therefore, the one-year, three-year, five-year, and tenyear survival rates for breast cancer in Iran were assessed using a meta-analysis. Materials and Methods: This systematic review and meta-analysis was based on valid Iranian sources including SID, MAGIRAN and IRANMEDEX, along with reliable English databases, namely, PUBMED and SCOPUS. In domestic databases, a search was conducted based on key words of breast cancer and survival rate, and in international databases, with "breast cancer" and the equivalent of "neoplasm" of Mesh Word, "survival rate" and "Iran." Then all reviewed papers and theses which met the inclusion criteria were selected for investigation. To conduct the analysis STATA 11.2 software and random-effects models were used. Results: In 24 studies, 22,745 participants were included. The one-year, three-year, five-year and ten-year survival rates were 0.956, 0.808, 0.695 and 0.559, respectively. The minimum and maximum survival rates for 5-years were 0.48 and 0.87. The average age of the onset of the disease was 48.3. Conclusions: As in Iran, since the onset of the disease is at low age, in spite of the relatively high survival rate as compared to other cancers, prevention and screening programs at early age for early stage diagnosis seems necessary.
Background: Mammography is a valuable tool for early diagnosis of breast cancer in asymptomatic women. Considering the high prevalence of breast cancer in Iranian women and the low participation in mammography screening program, the purpose of this study was to investigate the factors affecting frequency of mammography screening in women over 40 years of age using zero-. Methods: In this study, the required information about number of performing mammography in women's' lifetime, demographic characteristics and behavioral risk factors were obtained through interview based on a researcher-made questionnaire. To investigate the factors affecting mammography, zero inflation Poisson regression models were performed using Win Bugs software. Results: The mean (SD) age of women participating in this study was 49.87 (6.76). 77% of the participants have never undergone mammography, 8.9% once, 6.9% twice, 6.7% three times, and 0.5% more than three times. Age had a positive effect on the number of mammograms in the women who have perform mammograms at least once. Having a family history of cancer and breast cancer, middle compared to low economic status, higher compared to low education and menopause were significantly associated with lower probability of never performing mammography. Conclusion: Given the relatively low participation of women in mammography, more facilities are needed for high risk women (aged 40-70) to facilitate the diagnosis process.
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