about 80% within 2 years. 2 Radiotherapy, photodynamic therapy bleomycin, steroid, and 5-FU injections can be combined with surgery, but there are scarce information concerning specific techniques, doses, or success rate. [2][3][4] Many studies have reported successful treatment with laser therapy, whose best results are obtained, when using intense pulsed light or fractional lasers. However, when used in monotherapy, laser therapy shows recurrence rates similar to conventional surgery alone (45%-100%). 5 We present a new technique for recalcitrant auricular keloids, which combines surgery, contact cryotherapy, intralesional injections of 5-FU, and TA.

No abstract

Melanocytic matricoma with atypical features is a rare, biphasic adnexal neoplasm displaying hair matrix differentiation, with only 3 reported cases worldwide. Generally, the lesion comprised a solid matrical and supramatrical cell proliferation, admixed with intermediate cell aggregates with sparse anucleated "shadow cells" and a prominent pigmented melanocytic hyperplasia. We report the case of a 78-year-old man with a slow-growing crusted lesion on the frontal left scalp, which in a matter of 1-2 months became a 0.6 cm well-defined, black purplish exophytic nodule. Histopathologically, the lesion presented a well-circumscribed border with a nodular dermal growth pattern, presenting different architectural features varying from benign pilomatricoma-like changes to atypical features such as moderate-to-high nuclear pleomorphism in both basaloid (matrical/supramatrical) and epidermal (keratinous) components. Strong nuclear and cytoplasmic positivity for b-catenin was observed in matrical cells, whereas prominent cytoplasmic membrane positivity for Melan-A in dendritic melanocytes. Owing to the evidence of atypical cytological features, we propose the "atypical/borderline" category of melanocytic matricoma as part of a possible spectrum among matrical neoplasms. Pathologists should be aware of any atypical histopathological features while reporting cases due to their potential malignant transformation.