In order to effectively promote the efficiency of retail enterprises, the innovation path of business administration based on artificial intelligence is studied. Through a questionnaire survey, collect the relevant data of retail enterprise value network, business model innovation, and enterprise benefits, and through regression analysis. The experimental results show that before the business model innovation, the coefficients of internal value network innovation and external value network innovation are 0.413 and 0.258, respectively. After the business model innovation is added, the coefficients of the two are reduced to 0.208 ( p = 0.012 < 0.05 ) and 0.113 ( p = 0.005 < 0.01 ). In addition, the coefficients of the two dimensions of business model innovation are significant at the 1% level. Conclusion. Both internal value network innovation and external value network innovation have a significant positive impact on the functional business model innovation and artificial intelligence business model innovation of retail enterprises. Functional business model innovation and artificial intelligence business model innovation have a significant positive impact on the financial and market benefits of retail enterprises. Internal value network innovation and external value network innovation have a significant positive impact on the financial and market benefits of retail enterprises. Business model innovation plays an intermediary role in the relationship between internal value network innovation, external value network innovation, and the financial and market benefits of retail enterprises.