The United Nations' Sustainable Development Goals (SDGs) are an urgent call for action by all countries that provide a global framework for achieving global development while balancing social, economic, and environmental sustainability. SDGs are addressed to all actors in society, but both academia and professional recognize the particular importance of businesses. However, research is still needed to understand the role of companies as sustainable development agents. Relying on Scopus database consultation, the current research adopts an interdisciplinary systematic literature review to investigate, analyze, and present state-of-the-art academic literature on the role of businesses in tackling SDGs. The final sample comprises 101 papers published between 2015 and 2020. It provides evidence that the main topics discussed by scholars are related to aspects of strategy execution. Recognizing different streams that are currently unexplored-despite strictly related to strategic business activities and to the sustainable development as a whole-the study provides many insights for future research on business and SDGs.