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Penelitian ini adalah pettelitian retrospektif yang nenggunakan data dari Sub Unit Patologi Anatottti, Instalasi Bedah Sentral, RS Dr-CiptoMangunkusuno,nulaiJanuarilggosanpaiDesetnberlggl.Selannduatahundilakukan20Tkasuspotongbekujaringan tiroid' Dari 185 kasus yang diteliti,ditet,tukan 157 kasus (84,9%) kelainan jinak dan 28 kasus (15,1%) ganas. pada sediaan parafin ditenukan 158 kasus (85,4%) jinakdan 27 (14,8%) ganas. Terdapat positif palsu 3 kasus dannegatif patsi 2 kasus-Sensitivitas ntencapai 92,6%, spesifisitas 98,1%, ketepatan keseluruhan 97,3%, nilai ratnalan positif 89,3% dan nilai ratnalan negatif 9g,7%. Dengan analisis tersebut disimpulkan bahwa ketepatan diagnosis potong bekujaringan tiroid cukup tinggi, sehingga cara ini tnasih diperiukan dalatn nenentukan kcganasan tiroid dengan cepat.

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Introduction. Prevalence of the lymph node metastases of central neck compartment in papillary thyroid carcinoma (PTC) and its correlation with regional metastatic remains high. There are pros and cons on central neck dissection which is thought to solve the problem. Selection of appropriate patient to undergo central neck dissection is then essential. Thus, predictive factors were very useful in such selection, and we run a study aimed to find out the clinicopathological predictive factors for metastases of central compartment in subjects treated in Cipto Mangunkusumo General Hospital. Method. Data of 62 cN0 papillary thyroid carcinoma (PTC) subjects who underwent central neck dissection were collected consecutively and retrospectively studied. The correlations between clinicopathological factors such as age. Gender, tumor size, extra thyroid extension. Distant metastasis, completeness of resection, histopathology variant, lymphovascular invasion and central compartment metastases were the variables analyzed. Chi square. Fischer exact and stratification test were used. Significance found if p value of <0.05 with 95% confidence interval. Results. In this study, the prevalence in our hospital is 20.9%. The clinicopathological factors that statistically showed significance were the positive lymphovascular invasion (OR=14.40; p<0.05), tall cell variant (OR= 14.00; p <0.05), positive extra thyroid extension (OR=10.44; p<0.05) and age ≥45 years (OR= 9.47; p <0.05). Lymphovascular invasion showed a higher OR (OR=14.40). Conclusion. The lymphovascular invasion, tall cell variant, extra thyroidal extension and age might be the predictors for central compartment lymph node metastases in cN0 PTC patients. However, lymphovascular invasion has the highest risk factor for central neck compartment metastases.

Keganasan tiroid dapat ditemukan sekitar 5% dari kasus dengan nodul tiroid. Untuk penatalaksanaan kasus nodul tiroid perlu membedakan kasus jinak dari yang ganas. Biopsi aspirasi jarum halus (BAJaH) dilakukan praoperasi sedangkan potong beku dilakukan pada saat operasi. Tujuan tulisan ini ialah mengevaluasi ketepatan diagnosis pemeriksaan BAJaH serta PB bersama sitologi imprint (PB+I) pada kasus-kasus nodul tiroid di Departemen Patologi Anatomik FKUI-RSCM. Penelitian ini merupakan uji diagnostik menggunakan data arsip klinikopatologik di Departemen Patologi Anatmik FKUI-RSCM selama tahun 1999-2003. Spesimen dengan kelengkapan data hasil pemeriksaan BAJaH; data hasil pemeriksaan potong beku disertai sediaan sitologi imprint, serta sediaan histologik terfiksasi formalin dari bahan biopsi / operasi tiroid yang sama, digunakan dalam penelitian ini. Sensitivitas,