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Background: Variations in the distribution of health facilities have resulted in differences in health outcomes within the administrative districts of Ghana of which the Lower Manya Krobo Municipality (LMKM) is no exception. Aim: The primary objective of this study was to examine the distribution of health care resources in the Lower Manya Krobo Municipality in the Eastern Region of Ghana. Methods: A single case study approach was adopted, involving all health resources, facilities, and their supporting service centers in the LMKM. All functional health facilities in the municipality during the time of the study were included in the study. The study partly utilized records of generated coordinates using the Geo-positioning system (GPS) of other resources and services. Results: The Municipality had a total of 16 health facilities and 29 supporting centers. There were 285 clinical health workers in the municipality. Odumase and Akuse, had higher percentages of clinical health personnel. The population per single health worker ratio for the whole municipality was found to be 13201:1. Agomanya had the highest number of facilities and support centers. The population per health facility ratio was 15,086 per facility.Conclusion: The study demonstrated disparities in the distribution of health facilities across the municipality. There is a need to ensure the distribution of all health resources corresponds to the population size and the health needs of the Lower Manya Krobo Municipality.