Medical records of a total of 26 patients with an age of <18 years who were treated with Nb UVB phototherapy for vitiligo between January 2009 and January 2014 at our clinic were evaluated retrospectively. Age, sex, duration of the disease, presence of family history, comorbidities, skin type, vitiligo subtype, topical treatment the patient had used, duration of Nb UVB treatment, total number of sessions, total cumulative dose, response to treatment, and adverse effects secondary to the treatment were recorded. Lesions were grouped as generalized, focal, and acrofacial according to the Fitzpatrick classification (5). Phototherapy protocolWritten informed consent was obtained from all parents and standard phototherapy precautions were taken in all cases; eyes were covered and the genitals were protected. A Daavlin cabin (Daavlin, Bryan, OH, USA) with a Philips TL-01/100W fluorescent light (Philips Company, Eindhoven, the Netherlands) was used as the phototherapy source. The Nb UVB treatment was administered twice Background/aim: Narrowband UVB (Nb UVB) treatment is commonly used for the management of psoriasis and atopic dermatitis, and is less often used for vitiligo in children. The aim of this study was to evaluate the efficacy and short-term safety of Nb UVB phototherapy in children diagnosed with vitiligo retrospectively Materials and methods: A total of 26 patients younger than 18 years with the diagnosis of vitiligo and managed with Nb UVB phototherapy as documented in archive records were evaluated. Clinical response was assessed according to repigmentation of the lesions: good response when there was more than 75% repigmentation, moderate response when there was 25%-74% repigmentation, poor response when repigmentation was less than 24%, and unresponsive when there was no pigmentation and new lesions occurred.Results: A total of 26 patients received Nb UVB treatment; 14 were girls and 12 were boys. The age at onset of the disease varied between 2 and 18 years, with a mean age of onset of 10.07 ± 4.53 years. Repigmentation rate of >75% was detected in 45.4% of cases. Conclusion:Nb UVB phototherapy seems to be a well-tolerated effective and safe treatment option in children, especially those unresponsive to topical treatment and those with widespread lesions. However, long-term risks such as photocarcinogenesis and photoaging should kept in mind.
ÖzGünümüz vergi hukukunun köklerini ve ruhunu özellikle Tanzimat sonrası olmak üzere geç dönem Osmanlı vergi reformlarında bulmak mümkündür. Bu tarihî devir, anayasal vergilendirme ilkelerinin nasıl bir değişim yarattığının aşama aşama gözlenebildiği bir gözlem alanı olarak esaslı bir önem ve elverişlilik arz etmektedir. Bu çalışma, işbu döneme günümüzde ayrıntılı bir şekilde tanımlanmış olan anayasal vergilendirme ilkeleri ışığında bakmayı amaçlamıştır. Bu çerçevede, öncelikle vergilendirme ilkelerinin neler olduğu ortaya konulmaya çalışılmış, daha sonra klasik Osmanlı vergi sisteminin bu ilkeler bakımından ne durumda olduğu kısaca değerlendirilmiş, ardından vergi konusundaki Tanzimat döneminden Meşrutiyet dönemini de kapsayacak biçimde Cumhuriyete kadarki anayasal ve diğer hukukî düzenlemeler ve somut tarihî vakıalar ve gelişmeler yorumlanarak nihayetinde ilkelere ne ölçüde riayet edildiği hakkında bir sonuca varılmaya çalışılmıştır. AbstractIt is possible to find the roots and spirit of today's tax law in late Ottoman tax reforms, especially after Tanzimat. This historical period has great importance and convenience as an observation area where the principles of constitutional taxation can be observed step-by-step. This study aims to look at this period in the light of the principles of constitutional taxation that are defined comprehensively today. In this context, firstly, the principles of taxation were tried to be explained, secondly the traditional Ottoman tax system was shortly evaluated in terms of these principles, and then the constitutional and other legal regulations and concrete historical cases and developments from the Tanzimat period to the
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