Comparison of research results is difficult as studies focus on different seizure types, timing (night versus day) and patients (adult versus pediatric patients). Nevertheless, we are convinced that the most effective seizure detection systems are multimodal, combining for example detection methods for movement and heart rate, and that devices should especially take into account the user's seizure types and personal preferences.

Epileptic seizure detection is traditionally done using video/electroencephalography monitoring, which is not applicable for long-term home monitoring. In recent years, attempts have been made to detect the seizures using other modalities. In this study, we investigated the application of four accelerometers (ACM) attached to the limbs and surface electromyography (sEMG) electrodes attached to upper arms for the detection of tonic-clonic seizures. sEMG can identify the tension during the tonic phase of tonic-clonic seizure, while ACM is able to detect rhythmic patterns of the clonic phase of tonic-clonic seizures. Machine learning techniques, including feature selection and least-squares support vector machine classification, were employed for detection of tonic-clonic seizures from ACM and sEMG signals. In addition, the outputs of ACM and sEMG-based classifiers were combined using a late integration approach. The algorithms were evaluated on 1998.3 h of data recorded nocturnally in 56 patients of which seven had 22 tonic-clonic seizures. A multimodal approach resulted in a more robust detection of short and nonstereotypical seizures (91%), while the number of false alarms increased significantly compared with the use of single sEMG modality (0.28-0.5/12h). This study also showed that the choice of the recording system should be made depending on the prevailing pediatric patient-specific seizure characteristics and nonepileptic behavior.

The most effective seizure detection systems are multimodal. Such systems should also be comfortable and low-power. The body signals and modalities on which a system is based should take account of the user's seizure types and personal preferences.

No abstract

Nocturnal home monitoring of epileptic children is often not feasible due to the cumbersome manner of seizure monitoring with the standard method of video/EEG-monitoring. We propose a method for hypermotor seizure detection based on accelerometers attached to the extremities. From the acceleration signals, multiple temporal, frequency, and wavelet-based features are extracted. After determining the features with the highest discriminative power, we classify movement events in epileptic and nonepileptic movements. This classification is only based on a nonparametric estimate of the probability density function of normal movements. Such approach allows us to build patient-specific models to classify movement data without the need for seizure data that are rarely available. If, in the test phase, the probability of a data point (event) is lower than a threshold, this event is considered to be an epileptic seizure; otherwise, it is considered as a normal nocturnal movement event. The mean performance over seven patients gives a sensitivity of 95.24% and a positive predictive value of 60.04%. However, there is a noticeable interpatient difference.