Takayasu's arteritis is a rare, chronic progressive panarteritis involving the aorta and its main branches. Anesthesia for patients with Takayasu's arteritis is complicated by their severe uncontrolled hypertension and end-organ dysfunction resulting from hypertension, stenosis of major blood vessels affecting regional circulation, and difficulties encountered in monitoring arterial blood pressure. We report two cases of anesthetic management in pediatric patients who had Takayasu's arteritis. One was a case of general anesthesia for an ophthalmic laser operation and the other was a case who needed sedation during an aortic stent insertion.