BACKGROUNDChronic otitis media is defined as chronic inflammation of mucoperiosteal lining of part or whole of the middle ear cleft characterized by ear discharge, a permanent perforation of tympanic membrane and impairment in hearing. It is one of the most common causes of deafness and recurrent ear infections in developing countries like India. In bilateral disease, hearing handicap becomes more evident. Surgical management of perforation is needed if perforation fails to heal by conservative therapy. The objectives of this study were-1) to study the graft uptake by different graft materials in myringoplasty. 2) to evaluate hearing improvement by different graft materials in myringoplasty. MATERIALS AND METHODSA total of 100 patients with CSOM tubotympanic type were selected who underwent myringoplasty with 5 types of graft materials, 1) temporalis fascia, 2) cartilage, 3) periosteum, 4) perichondrium, 5) fascia lata in Government ENT Hospital, Andhra Medical College, Visakhapatnam, during November 2016 to April 2018 were studied during a period of one and a half year, for sex and age variations, graft uptake, hearing improvement.