Background: India is experiencing a rapid health transition and is projected to become a major reservoir of chronic diseases like diabetes and hypertension and 25-40% of these subjects may develop chronic kidney disease (CKD) and end stage renal disease (ESRD) Objectives: To analyse the drug utilisation pattern of antihypertensives in patients with Chronic Kidney Disease. Materials and Methods: A cross sectional study conducted in patients with Chronic Kidney Disease in a tertiary care hospital over a period of 6 months in 2014. The information regarding demographic details and antihypertensive drugs prescribed were collected from the patient's case records and the data was compiled and subjected to statistical analysis Results: Total of 95 case records was analyzed. CKD was more common in males, with male to female ratio of 4:1. 49.47% of the patients belonged to the age group of 40 -60 years followed by 31 -40 years (26.32%). Among the antihypertensive calcium channel blockers, diuretics, centrally acting antihypertensives, β blockers, α blockers, vasodilators, α+β blockers and ACE inhibitors were routinely used. Conclusion: Combination of various antihypertensive drugs were used in CKD patients undergoing dialysis.