Background: Ovarian tumors account for about 30% of female genital tract tumors and is fourth leading cause of cancer deaths in females. This study was conducted to evaluate the frequency and distribution of histological types of ovarian tumors. Methods: This was a retrospective seven years observational study based on histomorphological evaluation of 151 ovarian tumours received in department of pathology. Statistical analysis was done and chi-square test was used to see the association. Results: Out of 151 cases, 149 were primary ovarian tumors and two were metastatic tumors to ovary. There were 124 benign tumors, one was borderline and 26 were malignant.Most common age group affected was 31 to 45 years. Benign tumors were common in 16 to 30 years age group, whereas malignant tumors in 46-60 years. For all age group, benign tumors were more common than malignant tumors. Surface epithelial tumors (72.2%) were the most common followed by germ cell tumors (19.9%) and then sex cord stromal tumors (6.6%). Serous cystadenoma (41.93%) was the most common benign tumor followed by mucinous cystadenoma (32.25%). Serous cystadenocarcinoma (38.46%) was the most common malignant tumor. Most common germ cell tumor was mature cystic teratoma (73.3%) and granulosa cell tumor (50%) was the most common sex cord stromal tumor. Conclusion: Diagnosis of neoplastic ovarian lesions requires correlation between clinical, gross and microscopy features as the morphologic diversity of ovarian tumors poses many challenges. In difficult cases, immunohistochemistry and molecular diagnosis may be often required.

Introduction: Thrombocytopenia defined as platelet count below 1,50,000/ul. This fall in platelet count may be due to decreased production, increased destruction and pooling of platelets. The platelet parameters include platelet count, mean platelet volume (MPV), platelet distribution width (PDW) obtained by automated cell counters. These help in knowing the pathomechanism of myriad cases of TCPs. Hence the present study was undertaken to know the variations and correlations of platelet parameters in various causes of TCPs. Materials and Methods: 700 blood samples of patients with platelet count <1,50,000/ul and 600 control group samples with normal platelet count >1,50,000/ul were studied. Hematological analysis was done by Sysmex KX-21. Platelet parameters of all the cases and control group were noted. The cases were grouped into various categories of A, B or C depending on mechanism of decrease in platelets. Data was analyzed and tested for statistical significance using one-way ANOVA and post hoc testing using Tukey's test. Results: Majority of the cases in the present study were in group A (75.3%), followed by group B (23.9%) and group C (0.6%). A higher value of MPV (10.15±1.30 fl) and PDW (14.44±2.35%) was found in group A compared to other categories. Significant results of MPV and PDW values were seen in group A and group B category. Conclusion: Platelet parameters like MPV and PDW obtained by automated cell counters together with platelet counts help us to know the pathomechanism of various causes of TCPs which inturn provides pivotal information for better management.

Renal adysplasia is rare, occurring in only one per 10,000 births. Ultrasonography at 21 weeks of gestation in 33 years woman showed cystically enlarged left kidney in fetus and absent right kidney in fetus for which the pregnancy was terminated. On fetal autopsy, left kidney showed multiple tiny cysts. Microscopy of the left kidney showed features of dysplasia and confirmed the absence of right kidney and bilateral ureters. The diagnosis of renal adysplasia (multicystic dysplasia of left kidney and agenesis of right kidney) was made. This case is presented for its rarity.

Primary squamous cell carcinoma (SCC) of breast is a pure epithelial type of metaplastic carcinoma accounting for less than 0.1% of all breast cancers. A 70 year female presented with left breast lump of 4 months duration. Toilet mastectomy was done. Histopathology proved it to be primary SCC (large cell keratinizing) of breast. On immunohistochemistry, tumor cells were positive for pancytokeratin and epidermal growth factor receptor and negative for estrogen, progesterone receptors and HER-2/neu (triple negative). On follow up, after 1 month, patient presented with recurrence and metastasis to ipsilateral axillary lymph nodes. This case is presented for its rarity.