INTRODUCTION: The hepatitis B virus (HBV) is transmitted through corporal fluids as infected people’s blood and semen. Thus, sexual intercourse, blood transfusion, accidents with sharp materials are some of the main mechanisms of transmission of this virus. The HBV has tropism for hepatic cells and the infection by the virus can evolve on variable clinical conditions. The vaccine against hepatitis B has been available on the SUS (Brazilian Unified Health System) since 1998 and is an important collective prevention strategy. The present research aims to perform a sociodemographic evaluation of the hepatitis B diagnoses between the years 2007 and 2018, and to correlate it with the advances of the vaccination coverage in Brazil against hepatitis B. MATERIALS AND METHODS: This is an ecological study, retrospective and descriptive study that it has as methodology the use of secondary data from Sistema de Informação de Agravos de Notificação (SINAM). The sample was composed of all acute hepatitis B’s diagnoses in Brazil during the period from 2007 to 2018, totalizing 21432 records. In the research, the following variables were used: sex, age group, skin color/race, marital status, and schooling. RESULT AND DISCUSSION: This study has demonstrated that the male gender, as well as the brown population represents the largest number of cases. From the evaluation of the variables age and schooling, it was concluded that the population at the age group that, in general, is sexually active (from 20 to 39 years) is the most affected, and the population that presents low schooling characterizes the majority of individuals infected with HBV. FINAL CONSIDERATIONS: It is necessary to expand vaccination coverage by identifying the weak points of vaccination activity, besides the supply of the vaccine, location and adequate schedule to help the health system’s user accession. It is essential that the public policy of information and the campaigns are also directed to health professionals.

INTRODUCTION: Self-inflicted injuries may be classified suicidal behavior or self-harm. Regarding suicidal behavior, self-inflicted actions, which cause harm to the individual, involve ideation, attempt and suicide itself. Due to taboos related to suicide, public health problem and multifaceted psychosocial phenomenon, the perspectives of care and prevention are still limited in different health scenarios. This research aims to present a sociodemographic understanding of the phenomenon of suicide, promoting reflections that can improve therapeutic care, as well as subsidize preventive and health promotion proposals. METHODOLOGY: This is an ecological, descriptive and retrospective study whose methodology was the use of secondary data from the Mortality Information System (SIM). The sample consisted of all deaths secondary to voluntarily self-inflicted injuries, in Brazil, during the period 1996 to 2019, totaling 222,232 records. In the research, the following variables were used: Gender, Age, Color/Race, Marital Status and Education. RESULT AND DISCUSSION: men were the ones who died the most from self-harm and use more lethal methods to perform these injuries, although there are more suicide attempts among women. With regard to age group, most people who committed suicide were adults, aged between 20 and 59 years. However, it was noticed that the elderly and adolescents, in recent years, have become groups that are more vulnerable to suicide attempts. FINAL CONSIDERATIONS: there was an increase in the number of deaths from self-harm in Brazil among the years considered. It is noticeable that self-harm is a public health problem and requires adequate care and prevention interventions, in addition to structural changes related to risk factors.

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RESUMOO mau-prognóstico da COVID-19 está relacionada ao desenvolvimento da tempestade de citocinas, por isso se observou a necessidade de investigar essa relação de causa e efeito que já causou tantas perdas e desgastes desde do início da pandemia. Assim, essa revisão sistemática tem como objetivo compreender esse problema e condensá-lo nesse trabalho. Para destacar esse fenômeno, foi realizado busca nas bases de dados PubMed, Science Direct e Frontiers in Immunology, usando os descritores específicos pelo DeCS, selecionando um total de 9 artigos. A análise desses artigos mostrou que o processo infeccioso na COVID-19 pode desregular a resposta imune ao contribuir para uma resposta hiper inflamatória sistêmica; além disso, observou-se o desenvolvimento de distúrbios no processo de coagulação do hospedeiro. Por fim, apesar dessa revisão condensar as principais referências sobre o desenvolvimento da tempestade de citocinas a partir da COVID-19, as pesquisas ainda são recentes, podendo variar algumas hipóteses futuramente.