Original J Bras Neurocirurg 22 (3): 95-99, 2011Júnior LCMC, Barros BP, Holanda MFC -Fatores de risco em pacientes com aneurismas intracranianos atendidos em um hospital de referência de Belém -PA. 95Fatores de risco em pacientes com aneurismas intracranianos atendidos em um hospital de referência de Belém -PA. Risk factors in patients presenting with intracranial aneurysmsassisted in a reference hospital in Belém -PA. SUMÁRIO Objetivo: Este estudo visa averiguar a influência de fatores de risco sobre a mortalidade no tratamento de aneurismas.Método: estudo retrospectivo, transversal e quantitativo com pacientes atendidos entre Janeiro de 2001 a Dezembro de 2010 em virtude de aneurismas cerebrais no Hospital Ophir Loyola. Prontuários foram utilizados como fonte para coleta de dados sócio-demográficos, sobre fatores de risco e sobre o aneurisma. Foi realizada análise descritiva seguida pelo cálculo do risco relativo de cada variável em relação ao tipo de alta.Resultados: Dentre 123 pacientes com 158 aneurismas, 72,36% eram mulheres, a idade média foi 46,5 ± 12,7, 38,21% eram hipertensos, 5,69% diabéticos, 21,95% tinha múltiplos aneurismas, 87,80% foram tratados de forma intervencionista, a taxa de letalidade foi de 12,20% e 90,24% dos aneurismas tinha sítio na circulação anterior. O risco relativo de morte foi de 5,14 para o tratamento conservador em relação ao intervencionista e 4,02 para os com 60 anos ou mais em relação aos que tinham menos de 60 anos. Conclusão:Considerando as características dos pacientes deste estudo sugere-se a necessidade de pesquisas que avaliem a eficácia da triagem em pacientes com risco, detectando os aneurismas antes de sua ruptura e modificando a história natural desta doença. ABSTRACTObjective: This study aimed to investigate the influence of several risk factors over mortality in aneurysms treatment. Methods:A retrospective, quantitative transversal study with patients treated was undertaken in the period of January of 2001 to December of 2010 with cerebral aneurysm diagnosis in the Hospital Ophir Loyola. Medical papers were used for the data extraction, including socio-demographic data, information about risk factors and about the aneurysm. A descriptive analysis was performed, followed by relative risk of each variable to risk of death. Results: One hundred and twenty three patients with 158 aneurysms were collected , with a female predominance of 72,36% ; mean age was 46,5 ± 12,7, 38,21% had arterial hypertension, 5,69% diabetes; 21,95% had multiple aneurysms, 87,80% were surgically treated with a mortality rate of 12,20%: 90,24% of aneurysms were in the anterior circulation. The relative risk for death was 5,14 for conservative treatment versus interventional treatment and 4,02 for age of 60 or greater against less than 60 years old. Conclusion:Considering the patients characteristics of this study, we suggest new prospective studies in order to assess the efficacy of screening in risky patients to detect the aneurysms before their rupture , in order to modify the natural his...
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