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Left ventricular function is the best individual predictor of mortality after acute myocardial infarction. After Acute Myocardial Infarction (AMI), a patient's prognosis is closely related to the extent of irreversibly damaged myocardium. The evaluation of infarct size after Acute Myocardial Infarction (AMI) is important for predicting the subsequent clinical course and to validate the effectiveness and clinical relevance of therapeutic interventions. REVIEW OF LITERATURECoronary artery disease is the leading cause of death worldwide. The global burden of cardiovascular disease is expected to increase in the coming years, as falling mortality rates from coronary artery disease in the Western world are more than offset by the continuing epidemiological transition in developing countries away from nutritional deficiencies and infectious disease towards chronic and degenerative pathologies, cardiovascular disease being the most prominent. MATERIALS AND METHODSThe study was carried out in a study group of consecutive 88 patients admitted in ICCU from March 2012 to August 2013 in the Department of Medicine of MAHATMA GANDHI MEMORIAL HOSPITAL, Warangal, satisfying the selection criteria (as per inclusion and exclusion criteria laid down). RESULTSThe study was carried out in a study group of consecutive 88 patients admitted in ICCU from March 2012 to August 2013 in the Department of Medicine of MAHATMA GANDHI MEMORIAL HOSPITAL, Warangal, satisfying the selection criteria (as per inclusion and exclusion criteria laid down). CONCLUSIONSerum troponin T concentration has a strong negative correlation with left ventricular ejection fraction after first acute myocardial infarction and hence can be used to assess the LVEF in patients with first myocardial infarction. A level of >3.24 μg/mL provided a good indication for LVEF below 50% with a sensitivity of 91.67% (CI 80 to 97.7) and specificity of 92.5% (CI 79.6 to 98.4) and thus can identify patients with higher risk. KEYWORDSAcute Myocardial Infarction.HOW TO CITE THIS ARTICLE: Bhaskar P, Rao B, Naveen. Assessment of left ventricular function using 12-lead ECG and cardiac troponin-T in correlation with 2D-Echo following new-onset myocardial infarction.